Management of Preterm Premature Rupture of Membranes

Authors

  • Lino Arturo Rojas Pérez 1 Facultad de Salud Pública, Carrera de Medicina, Escuela Superior Politécnica de Chimborazo, Panamericana Sur Km 1.5, código postal 060106, Riobamba, Ecuador. 2 ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • Blanca Herminia Cruz Basantes 1 Facultad de Salud Pública, Carrera de Medicina, Escuela Superior Politécnica de Chimborazo, Panamericana Sur Km 1.5, código postal 060106, Riobamba, Ecuador. 2 ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • Lino Arturo Rojas Cruz ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • Augusto Ernesto Rojas Cruz ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • Andrés Eduardo Rojas Cruz ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • María Daniela Villagómez Vega ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • Monica Julieth Espinoza Tello ProSalud Medical Center, Jacinto González 1951 y Rey Cacha, Código postal 060101, Riobamba, Ecuador.
  • Alexander Expósito Lara Facultad de Salud Pública, Carrera de Medicina, Escuela Superior Politécnica de Chimborazo, Panamericana Sur Km 1.5, código postal 060106, Riobamba, Ecuador.

DOI:

https://doi.org/10.47187/cssn.Vol15.IssEd.Esp.304

Keywords:

premature rupture of fetal membranes, amniotic fluid, therapeutics

Abstract

Introduction: Preterm Premature Rupture of Membranes (PPROM) is the rupture of the chorioamniotic membranes that occurs before the onset of labor in preterm pregnancies. Complications can include chorioamnionitis, prematurity, and other problems associated with these conditions. Objective: To determine the best treatment for cases of preterm premature rupture of membranes according to the most updated scientific evidence available. Methodology: A clinical question was formulated based on the PICO format: What is the most appropriate management for pregnant women with preterm premature rupture of membranes to prevent complications? this facilitated the search for scientific information. Biomedical databases such as PubMed, Web of Science, UpToDate, and DynaMed were used. Results: A total of 452 articles were in different databases. After applying filters, discarding duplicate articles, and excluding those that did not meet inclusion criteria, 36 scientific articles were used a source of information for this research. Discussion: Preterm premature rupture of membranes can cause complications that put maternal and perinatal health at risk. Diagnosis is based on the observation of amniotic fluid leaking through the cervical opening when a vaginal speculum is used, and in cases of uncertainty, immunochromatographic tests can be applied. Conclusions: Appropriate and timely management reduces the complications that can occur due to this pathology.

Downloads

Download data is not yet available.

References

Ehsanipoor R, Pettker CM. Prelabor Rupture of Membranes [Internet]. The Amerian College of Obstetricians and Gynecologists. 2020 [cited 2024 Feb 3]. Available from: https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2020/03/prelabor-rupture-of-membranes

Scorza W. Prelabor rupture of membranes at term: Management [Internet]. UpToDate. 2024 [cited 2024 Mar 14]. Available from: https://www.uptodate.com/contents/prelabor-rupture-of-membranes-at-term-management/print?search=ruptura+prematua+de+membranas&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

Duff P. Preterm prelabor rupture of membranes: Clinical manifestations and diagnosis [Internet]. UpToDate. 2024 [cited 2024 Feb 2]. Available from: https://www.uptodate.com/contents/preterm-prelabor-rupture-of-membranes-clinical-manifestations-and-diagnosis?search=ruptura prematura de membranas&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2

Duff P. Preterm prelabor rupture of membranes: Management and outcome [Internet]. UpToDate. 2023 [cited 2024 Feb 3]. Available from: https://www.uptodate.com/contents/preterm-prelabor-rupture-of-membranes-management-and-outcome?search=ruptura prematura de membranas&source=search_result&selectedTitle=3~150&usage_type=default&display_rank=3

Onwughara CE, Moodley D, Valashiya N, Sebitloane M. Preterm prelabour rupture of membranes (PPROM) and pregnancy outcomes in association with HIV-1 infection in KwaZulu-Natal, South Africa. BMC Pregnancy Childbirth. 2020 Apr 9;20(1).

Term Prelabour Rupture of Membranes (Term PROM) - CLINICAL GUIDANCE STATEMENT. R Aust New Zeal Coll Obstet Gynaecol. 2021;(December):1–4.

DynaMed. Preterm Premature Rupture of Membranes (PPROM) [Internet]. EBSCO Information Services. 2024 [cited 2024 Feb 3]. Available from: https://www.dynamed.com/condition/preterm-premature-rupture-of-membranes-pprom#GUID-4756ECA8-70CB-4902-96BD-70E9BBFD5FD0

Martins I, Pereira I, Clode N. A pilot randomized controlled trial of complete bed rest versus activity restriction after preterm premature rupture of the membranes. Eur J Obstet Gynecol Reprod Biol [Internet]. 2019 Sep 1 [cited 2024 Mar 17];240:325–9. Available from: https://pubmed.ncbi.nlm.nih.gov/31377461/

Pineles BL, Vial M, Castro T, Ghorayeb T, Ajishegiri O, Sadek S, et al. Ambulation for latency during expectant management of preterm prelabor rupture of membranes: a randomized controlled trial (AMBLE). Am J Obstet Gynecol MFM [Internet]. 2024 Jan 1 [cited 2024 Mar 17];6(1). Available from: https://pubmed.ncbi.nlm.nih.gov/37944668/

Mandy G. Preterm birth: Definitions of prematurity, epidemiology, and risk factors for infant mortality [Internet]. UpToDate. 2022 [cited 2022 Nov 27]. Available from: https://www.uptodate.com/contents/preterm-birth-definitions-of-prematurity-epidemiology-and-risk-factors-for-infant-mortality/print?search=parto prematuro&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2

Mandy G. Short-term complications of the preterm infant [Internet]. UpToDate. 2021 [cited 2022 Nov 27]. Available from: https://www.uptodate.com/contents/short-term-complications-of-the-preterm-infant/print?search=parto prematuro&source=search_result&selectedTitle=7~150&usage_type=default&display_rank=7

Mandy G. Long-term outcome of the preterm infant [Internet]. UpToDate. 2021 [cited 2022 Nov 28]. Available from: https://www.uptodate.com/contents/long-term-outcome-of-the-preterm-infant/print?search=parto prematuro&topicRef=4965&source=see_link

Spontaneous preterm birth: Overview of risk factors and prognosis - UpToDate [Internet]. [cited 2024 Mar 27]. Available from: https://www.uptodate.com/contents/spontaneous-preterm-birth-overview-of-risk-factors-and-prognosis/print?search=ruptura prematura de membranas&topicRef=6754&source=see_link

DynaMed. Premature Rupture of Membranes at Term (Term PROM) [Internet]. EBSCO Information Services. 2024 [cited 2024 Feb 3]. Available from: https://www.dynamed.com/condition/premature-rupture-of-membranes-at-term-term-prom#GUID-2C3541F9-4AEA-41D8-A60F-A27658020EEF

DynaMed. Chorioamnionitis [Internet]. EBSCO Information Services. 2024 [cited 2024 Feb 3]. Available from: https://www.dynamed.com/condition/chorioamnionitis#GUID-F99ABF60-38BE-42AB-B7EC-6039BFA4309E

McElrath T. Prelabor rupture of membranes before and at the limit of viability [Internet]. UpToDate. 2024 [cited 2024 Mar 14]. Available from: https://www.uptodate.com/contents/prelabor-rupture-of-membranes-before-and-at-the-limit-of-viability?search=ruptura+prematua+de+membranas&source=search_result&selectedTitle=4~150&usage_type=default&display_rank=4

Lee M-J, Guinn D. Antenatal corticosteroid therapy for reduction of neonatal respiratory morbidity and mortality from preterm delivery [Internet]. UpToDate. 2022 [cited 2022 Nov 14]. Available from: https://www.uptodate.com/contents/antenatal-corticosteroid-therapy-for-reduction-of-neonatal-respiratory-morbidity-and-mortality-from-preterm-delivery/print?search=%22Prenatal therapy with corticosteroids for lung maturation%22&source=search_result&select

Crowther CA, Ashwood P, Andersen CC, Middleton PF, Tran T, Doyle LW, et al. Maternal intramuscular dexamethasone versus betamethasone before preterm birth (ASTEROID): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Heal [Internet]. 2019 Nov 1 [cited 2022 Oct 16];3(11):769–80. Available from: https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(19)30292-5/abstract

Caritis S, Simhan H. Management of pregnancy after resolution of an episode of acute idiopathic preterm labor [Internet]. UpToDate. 2022 [cited 2022 Nov 14]. Available from: https://www.uptodate.com/contents/management-of-pregnancy-after-resolution-of-an-episode-of-acute-idiopathic-preterm-labor/print?search=%22Prenatal therapy with corticosteroids for lung maturation%22&source=search_result&selectedTitle=10~150&usage_type=de

Norwitz E. Preeclampsia: Antepartum management and timing of delivery [Internet]. UpToDate. 2022 [cited 2022 Nov 14]. Available from: https://www.uptodate.com/contents/preeclampsia-antepartum-management-and-timing-of-delivery/print?search=%22Prenatal therapy with corticosteroids for lung maturation%22&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2

Utama DP, Crowther CA. Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth. Cochrane Database Syst Rev [Internet]. 2018 Jun 14 [cited 2022 Oct 16];2018(6). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513564/

Dynamed. Preterm Labor [Internet]. EBSCO Information Services. 2022 [cited 2022 Nov 14]. Available from: https://www.dynamed.com/condition/preterm-labor

Grzeskowiak LE, Grivell RM, Mol BW. Trends in receipt of single and repeat courses of antenatal corticosteroid administration among preterm and term births: A retrospective cohort study. Aust New Zeal J Obstet Gynaecol [Internet]. 2017 Dec 1 [cited 2022 Oct 16];57(6):643–50. Available from: https://www.scopus.com/record/display.uri?eid=2-s2.0-85022188432&origin=resultslist&sort=plf-f&src=s&sid=9f372d3a51dac2ce1030ab3da5dc8bac&sot=b&sdt=cl&cluster=scosubjabbr%2C%22MEDI%22%2Ct%2Bscosubtype%2C%22ar%22%2Ct%2Bscolang%2C%22English%22%2Ct%2C%22Span

Hofer OJ, Harding JE, Tran T, Crowther CA, Crowther CA. Maternal and infant morbidity following administration of repeat dexamethasone or betamethasone prior to preterm birth: A secondary analysis of the ASTEROID Trial. PLoS One [Internet]. 2022 Feb 1 [cited 2022 Oct 15];17(2). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863260/

Jobe AH, Milad MA, Peppard T, Jusko WJ. Pharmacokinetics and Pharmacodynamics of Intramuscular and Oral Betamethasone and Dexamethasone in Reproductive Age Women in India. Clin Transl Sci [Internet]. 2020 Mar 1 [cited 2022 Oct 16];13(2):391. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070803/

McGoldrick E, Stewart F, Parker R, Dalziel SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev [Internet]. 2020 Dec 25 [cited 2022 Oct 15];2020(12). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094626/

Socha P, McGee A, Bhattacharya S, Young C, Wang R. Antenatal Corticosteroids and Neonatal Outcomes in Twins: A Systematic Review and Meta-analysis. Obstet Gynecol [Internet]. 2022 Jul 1 [cited 2022 Dec 7];140(1):20–30. Available from: https://journals.lww.com/greenjournal/Fulltext/2022/07000/Antenatal_Corticosteroids_and_Neonatal_Outcomes_in.5.aspx

DynaMed. Prevention of Group B Streptococcal Infection in the Newborn [Internet]. EBSCO Information Services. 2024 [cited 2024 Apr 4]. Available from: https://www.dynamed.com/management/prevention-of-group-b-streptococcal-infection-in-the-newborn#GUID-9EC8EC49-1CC0-4FEA-9359-CEAB23DE56D8

Baker C. Prevention of early-onset group B streptococcal disease in neonates [Internet]. UpToDate. 2023 [cited 2024 Feb 3]. Available from: https://www.uptodate.com/contents/prevention-of-early-onset-group-b-streptococcal-disease-in-neonates?search=ruptura prematura de membranas&source=search_result&selectedTitle=9~150&usage_type=default&display_rank=9

Silverman N, Turrentine M. Prevention of Group B Streptococcal Early-Onset Disease in Newborns. ACOG COMMITEE OPINION [Internet]. The Amerian College of Obstetricians and Gynecologists. 2019 [cited 2024 Mar 14]. Available from: https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2020/02/prevention-of-group-b-streptococcal-early-onset-disease-in-newborns

DynaMed. Cerebral Palsy (CP) [Internet]. EBSCO Information Services. 2022 [cited 2023 Jan 9]. Available from: https://www.dynamed.com/condition/cerebral-palsy-cp

Barkoudah E, Aravamuthan B. Cerebral palsy: Epidemiology, etiology, and prevention [Internet]. UpToDate. 2022 [cited 2023 Jan 5]. Available from: https://www.uptodate.com/contents/cerebral-palsy-epidemiology-etiology-and-prevention/print?search=neuroprotección fetal&source=search_result&selectedTitle=10~150&usage_type=default&display_rank=10

Barkoudah E, Aravamuthan B. Cerebral palsy: Classification and clinical features [Internet]. UpToDate. 2022 [cited 2023 Jan 9]. Available from: https://www.uptodate.com/contents/cerebral-palsy-classification-and-clinical-features/print?search=paralisis cerebral&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

Simhan H, Himes K. Neuroprotective effects of in utero exposure to magnesium sulfate [Internet]. UpToDate. 2022 [cited 2023 Jan 5]. Available from: https://www.uptodate.com/contents/neuroprotective-effects-of-in-utero-exposure-to-magnesium-sulfate/print?search=neuroprotección fetal&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

Wolf HT, Huusom LD, Henriksen TB, Hegaard HK, Brok J, Pinborg A. Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis. BJOG [Internet]. 2020 Sep 1 [cited 2023 Jan 10];127(10):1180–8. Available from: https://pubmed.ncbi.nlm.nih.gov/32237069/

DynaMed. Tocolytics for Treatment of Preterm Labor [Internet]. EBSCO Information Services. 2022 [cited 2023 Jan 9]. Available from: https://www.dynamed.com/management/tocolytics-for-treatment-of-preterm-labor

Downloads

Published

2024-09-20

How to Cite

Rojas Pérez , L. A., Cruz Basantes , B. H., Rojas Cruz , L. A., Rojas Cruz, A. E., Rojas Cruz, A. E., Villagómez Vega , M. D., Espinoza Tello , M. J., & Expósito Lara, A. (2024). Management of Preterm Premature Rupture of Membranes. LA CIENCIA AL SERVICIO DE LA SALUD Y NUTRICIÓN, 15(Ed. Esp.), C_93–103. https://doi.org/10.47187/cssn.Vol15.IssEd.Esp.304

Issue

Vol. 15 No. Ed. Esp. (2024): Edición Especial CIEM 2024

Section

Revisiones bibliográficas

License

Copyright (c) 2024 LA CIENCIA AL SERVICIO DE LA SALUD Y NUTRICIÓN

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Most read articles by the same author(s)

1 2 > >>