Fetal neuroprotection
DOI:
https://doi.org/10.47187/cssn.Vol14.Iss1.220Keywords:
neuroprotection, fetus, magnesium sulfateAbstract
Introduction. Childhood cerebral palsy involves a group of disorders of the central nervous system that produce motor dysfunction that affects muscle tone, posture, and movement. Objectives. To determine the best preventive treatment for infantile cerebral palsy in pregnant women at high risk of imminent preterm birth. Methodology. The clinical question under the PICO format was used: What is the most effective preventive treatment for the prevention of infantile cerebral palsy in patients at high risk of imminent preterm birth? The population is pregnant women at high risk of imminent preterm birth, the intervention is the administration of neuroprotection, the comparison is the non-administration of neuroprotection, and the result is the decrease in infant cerebral palsy. Results. To carry out this non-systematic review, 213 articles were obtained, of which 178 were discarded for not being within the inclusion criteria and 35 articles were obtained for the process of preparing this research. Discussion. The administration of magnesium sulfate as infant neuroprotection decreases the risk of cerebral palsy in newborns born between 24 to 31 weeks with 6 days. Conclusions. Magnesium sulfate is the most effective drug for the prevention of infantile cerebral palsy when administered for at least 4 hours in patients at high risk of imminent preterm birth between 24 and 31 weeks 6 days.
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