Evaluation and diagnosis of kartagener's syndrome bibliographic review

Abstract

Introduction: Kartagener's syndrome (KS) is a rare disease with a triad of clinical manifestations: sinusitis, bronchiectasis and complete or incomplete situs inversus, in the presence of primary ciliary dyskinesia. Objective: describe the main aspects of Kartagener's syndrome. Methodology: The respective bibliographic search of indexed journals was carried out in the main databases such as: SciELO, MedLine/Pubmed/PMC, Google Scholar and ScienceDirect. Results: The search found 96 articles from which different articles that did not meet the inclusion criteria were eliminated, concluding with the selection of 30 articles. Discussion: KS is a consequence of primary ciliary dyskinesia (PCD), which results in impaired mucociliary clearance and heightened susceptibility to respiratory tract infections. The clinical manifestations of this condition include chronic otitis media, rhinitis and hydrocephalus. The management of KS encompasses medical intervention with drugs such as mucoactive agents, steroids and antibiotics, in addition to surgical procedures. Conclusions: KS is an autosomal recessive inherited disease. If diagnosed from infancy and not overlooked, it is possible to avoid the conditions that determine the clinical triad of this pathology.